Derry City will have to overturn a 1-nil first leg deficit if they’re to reach the Conference League playoff round.
Tobol player Roman Asrankulov scored a screamer midway through the second half in Kazakhstan.
Michael Duffy squandered a gilt-edged chance to level the tie 12-minutes from time.
The return leg next week will be played at The Tallaght Stadium in Dublin as the Brandywell does not meet the criteria for hosting a third round game.