The N13 Letterkenny to Lifford Road has reopened between Manor Roundabout and Dromoghill after a fatal collision last night.
A man, aged in his 30s was a front seat passenger in one of two cars which collided at around 7pm at Carrickballydooey.
Both drivers are receiving treatment at Letterkenny University Hospital to what Gardai say are non-life-threatening injuries.
Gardai are urging anyone with information or dash cam footage to come forward.