The N56 between Falcarragh and Gortahork is closed as a result of a collision.
Gardai say diversions are in place, and traffic disruptions can be expected.
In a statement, Gardaí say they and the Emergency Services have been attending the scene of a traffic collision on the N56 close to Falcarragh, which happened at approximately 1.30 this afternoon.
No further details have been given.